BD FACSymphony™ A5 SE (Spectral Enabled) Cell Analyzer offers users flexibility of using spectral or conventional flow cytometry analysis
FRANKLIN LAKES, N.J., Sept. 22, 2021 – BD (Becton, Dickinson and Company) (NYSE: BDX), a leading global medical technology company, today announced the launch of a spectral-enabled cell analyzer, expanding current cell analyzer capabilities to at least 34 parameters with live spectral unmixing, enabling researchers to precisely analyze selected single cells from complex samples.
The new BD FACSymphony™ A5 SE Cell Analyzer is a fluorescence-activated, spectral-enabled cell analyzer that offers researchers the ability to choose between spectral or compensation-based cell analysis to meet different flow cytometry needs. It is an important addition to the extended family of BD FACSymphony™ Cell Analyzers and Sorters, including the recently announced BD FACSymphony™ A1 Cell Analyzer, which offers premium performance in a benchtop format. For existing users of the BD FACSymphony™ A5 Cell Analyzer, software and hardware upgrades are available to enable spectral analysis.
“By enhancing our BD FACSymphony™ A5 instrument technology with spectral-enabling capabilities, we are responding to the expressed needs of our customers and laboratories, who want the flexibility to perform both conventional and spectral flow cytometry analyses on a single instrument,” said Puneet Sarin, worldwide president of BD Biosciences. “Offering an analyzer with both spectral unmixing and compensation-based cell analysis gives customers the ability to transition to spectral analysis as needed and as their users are ready.”
With spectral unmixing, researchers have access to expanded dye capabilities to build larger panels or ease panel design efforts. Compensation-based analysis supports labs with existing protocols and users not ready to fully move to spectral analysis.
Spectral flow cytometry represents an alternative data acquisition and analysis strategy to conventional flow cytometry, providing flexibility of fluorescent label inputs without having to change filters, as well as the ability to multiplex more fluorescent labels in one multicolor sample. Spectral unmixing is a procedure that calculates the amount of each fluorophore present on a cell based on the full emission profile of each individual fluorochrome.